Utility of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in predicting acute-on-chronic liver failure survival

Abstract This study explored the predictive value of monocyte-to-lymphocyte ratio (MLR) and platelet–lymphocyte (PLR) in patients with acute-on-chronic liver failure (ACLF). A retrospective analysis was carried out on 40 ACLF from January 2018 August 2019 our hospital. The patient’s clinical information during hospitalization collected, their survivals were followed for 3 months. MLR PLR values compared, correlation between function indicators prognosis analyzed. We observed that levels survival death groups 0.521 (0.311, 0.827) 0.741 (0.442, 1.121), respectively. markedly enhanced group compared to ( P = 0.021). receiver operating characteristic curve (ROC) exhibited area under ROC 95% confidence interval 0.641 (0.528–0.757). Survival demonstrated 3-month high lower than low 0.001). Multivariate regression exposed independent prognostic factors ACLF. could be prospective prognosticative markers